Minnesota is known to be a hub for healthcare startups. The sector has grown over five-fold over the past 2 decades and the state is known to have the best healthcare ecosystem in the US.
Likewise, many international investors have announced plans to invest in the state.
Want to know who these investors are and how they are planning to invest in the United State’s Medial Alley?
Here is the list of the top angel investors in Minnesota, funding healthcare startups.
Top 8 Angel Investors in Minnesota Who Invest in Healthcare Startups
| Investor Name | Focused Sectors | Funding Stages | Notable Investments |
|---|---|---|---|
| Michael Pohl | AI, Human Resources, Internet, Software, Aerospace, Drones, Government, Automotive, Logistics | Early Stage | Ark Behavioral Health, Snyk, Plaid, Carta |
| Conor Green | AI, CRM, Healthcare, Machine Learning, Consulting, Developer Tools, IT Services, InsurTech | Seed/Early Growth | Updox, ConsumerMedical, Clinithink, Revel, MacroHealth |
| Patrick O'Shaughnessy | Fitness, Medical Cannabis, Healthcare Blockchain, Wearable Medical Devices | Early Stage | Eight Sleep, Perfect, Bottomless, HumanCo |
| Sean Stevens | Computer, Network Security, Software, Logistics, Retail Tech, Cyber Security | Early Stage | Advance Health, Senior Whole Health, Diabetes Care Group |
| Jason Hegrenes | Pharmaceuticals, Medical Devices, Biotechnology, Healthcare IT | Seed Stage | Healthify, Gusto, Nanit |
| Samuel Copman | Medical Devices, Biotechnology, Mental Health, Public Health, Personalized Medicine, Digital Therapeutics | Early Stage | Plaid, Headspace, Zapier |
| Douglas Mark | Healthcare, Payments, Software, Biotechnology, Health Diagnostics | Seed Stage | The Square, Alpha Audiology |
| Mark Edwards | Healthcare, Biotech, Manufacturing, Energy, Renewable Energy | Early Stage | Nextdoor, Aurora Solar, Notion |
Michael Pohl
- Focused Sectors: Artificial Intelligence, Human Resources, Internet, Software, Staffing Agency, Aerospace, Drone Management, Drones, Geospatial, Government, Mapping Services, Women Founded, Automotive, Information Technology, Logistics, Manufacturing, Health Care, Hospital, Personal Health, Risk Management, Women Led, Clinical Trials, SaaS, E-Commerce, Enterprise Software
- Present In: Minnesota
- Notable Investments: Ark Behavioral Health, Snyk, Plaid, and Carta.
Michael Pohl stands as one of Minnesota's most prominent angel investors, with a keen interest in startups addressing critical industry challenges through innovative technology. Since 2016, he has made around 30 investments, focusing on early-stage companies that have validated business models and demonstrate early traction.
As an investor, Pohl has worked at several high-profile firms in venture capital and private equity. He worked at Bessemer Venture Partners and later worked at The Carlyle Group in their technology-focused private equity division.
The average check size of Michael Pohl lies between $100,000 to $500,000.
Conor Green
- Focused Sectors: Artificial Intelligence, CRM, Health Care, Machine Learning, Consulting, Developer Tools, Information Technology, Information Services, InsurTech, Biotechnology, Genetics, Pharmaceutical, Women Founded, Medical, Wellness, Analytics, Personal Health, Clinical Trials, Life Science, Software, SaaS, mHealth, Neuroscience, B2B, B2C, Collaboration, Developer APIs
- Present In: Minnesota
- Notable Investments: Updox, ConsumerMedical, Clinithink, Revel, MacroHealth:
Conor Green is a famous healthcare investor with a strong background in venture capital and private equity. He began investing in startups in 2015 and has since funded over 25 early-stage companies. Green primarily invests in healthcare and tech-driven startups.
Before becoming an angel investor, Green worked at Sequoia Capital and Andreessen Horowitz. He selects startups through networking events and startup incubators and prefers companies that have a strong idea.
The investment range of Conor Green ranges between $100,000 to $500,000.
Patrick O'Shaughnessy
- Focused Sectors: Fitness, Medical Cannabis, Healthcare Blockchain, Wearable Medical Devices
- Present In: Minnesota
- Notable Investments: Eight Sleep, Perfect, Bottomless, and Human Co
Patrick O'Shaughnessy is also a seasoned angel investor with a background in finance and asset management. He began investing in startups in 2017 and has since funded over 20 companies.
Aside from his investment journey, O'Shaughnessy is the CEO of O'Shaughnessy Asset Management. Although he hasn't previously worked at a VC firm, Patrick O'Shaughnessy has always been an individual investor.
When investing in businesses, O'Shaughnessy focuses on startups with strong data-centric approaches, visionary leadership, and the ability to scale rapidly in large markets. The average check size of Patrick O'Shaughnessy lies between $50,000 to $250,000.
Sean Stevens
- Focused Sectors: Computer, Network Security, Software, Delivery Service, Logistics, Retail Technology, Same Day Delivery, Women Founded, Women Led, Cyber Security, SaaS, Security, Advertising, Marketing, Messaging, E-Commerce, Information Technology, Health Care, Home Health Care, Wellness, Asset Management, Craft Beer, Enterprise Resource Planning, Enterprise Software
- Present In: Minnesota
- Notable Investments: Advance Health, Senior Whole Health, Diabetes Care Group, Trilliant Health, Virtustream, Vocalocity, Half Off Depot, SecureWorks, NewsStand Inc., Wellcentive
With a strong focus on early stage startups, Sean Stevens is an active angel investor who has been funding startups since 2017.
He looks for startups that can show early traction, have a unique value proposition, and are positioned to dominate their market niche. He primarily invests in the early stages, where his capital and mentorship can have the greatest impact.
The average check size of Sean Stevens is around $300,000.
Jason Hegrenes
- Focused Sectors: Pharmaceuticals, Medical Devices, Biotechnology, Healthcare IT, Insurance, Clinical Research, Healthcare Consulting, Healthcare Services, Mental Health, Public Health
- Present In: Minnesota
- Notable Investments: Healthify, Gusto, and Nanit
Having more than 15 startups in his portfolio, Jason Hegrenes is also an individual angel investor who likes to invest in startups at the earliest stages. Hegrenes began his investor career in 2018 and worked at many prominent firms such as Bain Capital and General Catalyst.
Hegrenes is particularly interested in companies that bring innovative solutions to market, especially those that improve efficiency or create new consumer experiences. He values companies that are data-driven and have a clear path to profitability.
The investment range of Jason Hegrenes lies between $75,000 to $300,000.
Samuel Copman
- Focused Sectors: Medical Devices, Biotechnology, Mental Health, Public Health, Personalized Medicine, Digital Therapeutics, Regenerative Medicine, Precision Oncology, Telehealth for Chronic Diseases, Mental Health Apps, Elderly Care Technology, Medical Cannabis, Healthcare Blockchain, Wearable Medical Devices
- Present In:
- Notable Investments: Plaid, Headspace, and Zapier
Samuel Copman is a renowned and experienced angel investor in Minnesota who has a strong focus on healthcare startups. He started his angel investing journey in 2016 and has since funded over 20 startups.
When funding startups, Copman loves to invest in ventures that leverage technology to solve healthcare problems. He prioritizes startups with innovative solutions, robust business models, and driven founding teams.
Samuel Copman's investment range lies between $100,000 and $500,000.
Douglas Mark
- Focused Sectors: Healthcare, Payments, Software, Biotechnology, Health Diagnostics, Analytics, Electronics, Hardware, Industrial Manufacturing, Manufacturing, Energy, Renewable Energy, Sensor, Wireless, Chemical, Commercial, Industrial, Medical, Medical Device,
- Present In: Minnesota
- Notable Investments: The Square, Alpa Audiology
Funding startups since 2015, Douglas Mark is also an active angel investor who focuses on early-stage startups. With over 30 startups in his portfolio, Mark gravitates toward companies that create innovative solutions to large-scale challenges.
Serving as an investor at TPG Capital, Mark knows how to identify innovative companies and makes most of his investments through startup fundraisers. He also participates in startup accelerators and incubator events to meet with leaders who are shaping the future of healthcare.
The investment range of Douglas Mark ranges between $100,000 to $750,000.
Mark Edwards
- Focused Sectors: Healthcare, Biotech, Manufacturing, Energy, Renewable Energy, Sensor, Wireless, Chemical, Commercial, Industrial, Medical Device, Women Founded, Semiconductor, Product Design, Telecommunications, Women Led, CRM, Web Development
- Present In: Minnesota
- Notable Investments: Nextdoor, Aurora Solar, and Notion
Mark Edwards is also a seasoned angel investor with a focus on early-stage startups. He began investing in startups in 2014 and has since funded over 25 companies.
Edwards usually invests in startups at the seed stages, focusing on companies with strong founding teams, disruptive technologies, and the potential for rapid growth in large markets. He also prioritizes startups that have a clear competitive edge, a well-defined product-market fit, and strong unit economics.
The average check size of Mark Edwards lies between $100,000 to $500,000.
Wrap-Up:
Summing up, Minnesota is home to tons of angel investors who aren’t just focusing on making profitable investments but also providing mentorship to their portfolio companies.
As for founders who are planning to pitch to investors, always focus on adding value. Investors prioritize not only innovation but also founders who are coachable and prepared to scale responsibly. Present how your solution addresses a real market need, and don’t be afraid to ask for mentorship, it's often as valuable as capital.





