Top 6 Health Care Focused VC Firms and Angel Groups in New Hampshire in 2026

Borealis Ventures, based in Hanover, is the one firm on this list built around healthcare, with a focus on life sciences, digital health, and animal health. Alumni Ventures, 10X Venture Partners, and Millworks Fund II also back healthcare-related startups in New Hampshire, while Wasabi Ventures and York IE invest in the state's tech startups more broadly.

Building a healthcare startup isn't easy.

From medical devices and AI diagnostic tools to patient-focused SaaS platforms, one challenge remains the same:

Access to capital!

But not just any capital. What healthcare startups need is smart capital: investors who understand the terrain, believe in your vision and offer more than just a check.

So, are there VC firms in New Hampshire that can help you bring your healthcare innovation to life?

Yes, and we've already done the research for you. AngelMatch lists 90+ investors based in New Hampshire, and 20+ of them are tagged to health care.

In this post, we're breaking down the top 6 VC firms and angel groups in New Hampshire, from one healthcare specialist to broader early-stage investors with a New Hampshire base. Looking for individual investors instead? See our list of top angel investors in New Hampshire. Let's get started.

Which VC Firms in New Hampshire Invest in Healthcare Startups?

Here's a quick table to summarize the list:

Borealis Ventures

• Website: borealis.vc

• Focused Sectors: Life sciences platforms, digital health, and animal health

• Funding Stages: Seed and early stage, often the first institutional round

• Notable Investments: Adimab, Avitide, Compass Therapeutics, Ankyra Therapeutics

• Typical Check Size: $250,000 to $750,000 per company (per WaveUp)

Borealis Ventures was founded in 2002 by Philip Ferneau and Jesse Devitte. The firm is based in Hanover and has a presence in Boston. Its main focus is healthcare: life sciences platforms, digital health, and animal health.

Borealis has made more than 85 investments across five funds and has 24 portfolio exits, according to CB Insights and WaveUp. It is known for backing startups that come out of academic research, including companies tied to Dartmouth. Recent deals include a lead role in Jenga Biosciences in 2024 and a seed co-investment in ASTRA Therapeutics in 2025.

Borealis also manages funds built for New Hampshire founders. It partnered with the New Hampshire Business Finance Authority on the Granite Fund, whose notable successes include Avitide and Compass Therapeutics, and it runs the Vox Health Fund, a venture fund focused on life sciences and digital health. In 2018, it raised the Built Environment Innovation Fund, whose investments have included healthcare companies such as FidoCure.

Alumni Ventures

• Website: av.vc

• Focused Sectors: Broad, including health tech, enterprise software, consumer, and fintech

• Funding Stages: Pre-seed through Series B and beyond

• Notable Investments: SimpliSafe, Blue Note Therapeutics, Solsten

• Typical Check Size: $50,000 to $10 million or more (per Built In, 2022)

Alumni Ventures was founded in 2014 by Mike Collins and Luke Antal and is headquartered in Manchester. As of 2025, it managed roughly $1.5 billion in assets from about 11,000 individual and institutional investors, with a portfolio of more than 1,200 companies.

The firm runs funds tied to universities and to specific sectors, including a dedicated HealthTech Fund. Healthcare companies in its portfolio include Blue Note Therapeutics. Because Alumni Ventures invests across many sectors and stages, fit and check size vary by fund, so confirm which fund matches your startup before you reach out.

10X Venture Partners

• Website: 10xvp.com

• Focused Sectors: Medical technology, mobile, internet, wireless, security, and green technology

• Funding Stages: Seed and beyond

• Notable Investments: Kantum Pharma, SportsVisio

• Typical Check Size: $50,000 to $500,000, with larger investments and follow-ons possible

10X Venture Partners was founded in 2012 and is based in Manchester. It describes itself as a seed stage (and beyond) investment group that commits operational experience and dollars to its portfolio companies. PitchBook classifies it as an angel group and lists more than 50 investments, with the most recent in April 2026.

The group prefers companies in New England and lists medical technology among its sectors. It also co-invested in Kantum Pharma's Series A in 2021.

York IE

• Website: york.ie

• Focused Sectors: Software and AI companies

• Funding Stages: Labs, seed, and early growth

• Notable Investments: Terrantic

• Typical Check Size: Not published

York IE was founded in 2019 by Kyle York, Joe Raczka, and Adam Coughlin and is headquartered in Manchester. It calls itself an investment and operating firm: it backs software companies and also provides hands-on help with product development, go-to-market, and finance. CB Insights lists more than 90 investments, and in August 2024 the firm joined Terrantic's $3.5 million seed round.

Healthcare is not among York IE's stated focus areas. For more New Hampshire investors who fund software, see our list of top startup investors in New Hampshire who invest in software startups.

Wasabi Ventures

• Website: wasabiventures.com

• Focused Sectors: Early-stage technology, including SaaS, AI, education, and media

• Funding Stages: Pre-seed and seed

• Notable Investments: Right Now Technologies, Ustream

• Total Investments: Has built, financed, or advised 200+ startups

Wasabi Ventures was founded in 2003 by Chris Yeh and Tom "TK" Kuegler. It is a venture capital, incubator, and consulting firm that builds, finances, and advises early-stage technology startups. Kuegler leads its East Coast operation from Manchester.

Wasabi's other well-known ventures include PBworks and Etherpad. Healthcare is not among the focus areas listed on Kuegler's investor profile.

Millworks II Fund

• Website: millworksfund.com

• Focused Sectors: New Hampshire tech startups, including healthcare services and software

• Funding Stages: Seed

• Notable Investments: TendoNova (surgical devices), Datanomix

• Commitment: $600,000 per year for three years

Millworks Fund Series II was announced in 2017 as a $1.8 million public-private partnership. It is made up of 40 individual investors from fields that include banking, law, healthcare, and high-tech, along with the New Hampshire Business Finance Authority. PitchBook classifies it as an angel group based in Manchester.

The fund invested through the New Hampshire High Technology Council's annual TechOut competition and Alpha Loft's Accelerate NH program. Local business coverage reports that it supported TechOut through 2021 and that the New Hampshire Tech Alliance hopes another group will create a new fund, so confirm its current status before you pitch.

Wrap-Up:

Breaking into healthcare is hard. Breaking into it with funding is even harder.

But if New Hampshire proves one thing, it's this: innovation can thrive anywhere with the right people behind it.

From healthcare specialist Borealis to broader players like Alumni Ventures and 10X Venture Partners, the state has real capital, mentorship, and opportunity for founders bold enough to build.

So do your homework. Get your deck tight with examples from our pitch deck database. Reach out, and let our investor outreach email generator help with the first message.

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